| abstract |
(57) Summary The present invention provides an oxazinoquinolone derivative having a ring connecting the 4-position (N-4) and the 11-position (C-11). More particularly, the present invention provides compounds of formula I: The compound represented by these is provided. Because of the unique position of the chloro substituent on N-phenylmethyl of formula I, the compounds of the present invention and their pharmaceutically acceptable salts are useful as antiviral agents, particularly agents against the herpes family of viruses. Thus, the present invention also provides methods for treating or preventing herpesvirus infections, particularly human cytomegalovirus infections, and pharmaceutical compositions containing a compound of formula I. |