http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003510312-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-16 |
| filingDate | 2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2003510312-A |
| titleOfInvention | Process for producing substituted phenylsulfonylureas from sulfonyl halides |
| abstract | (57) Abstract: The present invention relates to a compound of the formula (I) or a salt thereof, wherein Q, X * , Y, Z, R, R 1 , R 2 and R 3 have the meaning described in claim 1. It relates to a manufacturing method. This method comprises: a) ammonolysis of compound (II) in which Hal = halogen atom to give compound (III) or (a1) reaction, preferably (1) optionally halogenated aromatic hydrocarbon [solvent (1) and (2) a step in which an organic solvent mixture comprising a polar aprotic solvent [Solvent 2] in a weight ratio of [Solvent 1]: [Solvent 2]: 20: 1 is used, (b) Compound (III) To give the phenylsulfonyl isocyanate of formula (IV) or (b1) if X * = halogen, the reaction is preferably catalyzed using phosgene in an organic solvent with R 1 equal to hydrocarbon Carrying out with or without the addition of an amine base in the presence of an isocyanate of the formula R 1 -NCO, (c) transforming the resulting compound (IV) in an organic solvent with an amino heterocycle H 2 N-Het ( Het = heterocycle as defined in (I)) ) Or their salts, or (c1) carrying out the reaction in a solvent mixture of an optionally halogenated aromatic hydrocarbon and a polar aprotic solvent, preferably having a boiling point above 110 ° C. It is characterized by. At least one of the preferred sub-steps (a1) to (c1) is performed in the method. Embedded image |
| priorityDate | 1999-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 159.