| abstract |
(57) [Summary]nThe present invention relates to novel adjuvant systems containing a polyoxyethylene alkyl ether or ester surfactant in combination with at least one additional nonionic surfactant. Preferably, the additional nonionic surfactant is octoxynol (TRITON ™ series). The present invention provides the novel adjuvants, vaccines containing them, methods of making them, and their formulation in vaccines. Also provided is the use of the adjuvant or vaccine of the invention in the prevention or treatment of a disease. |