http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003508451-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2003508451-A |
| titleOfInvention | Single-stranded oligonucleotide mutation vector |
| abstract | (57) [Summary]nThe present invention relates to introducing a predetermined genetic change into a target gene of a living cell by introducing an oligodeoxynucleotide encoding the predetermined change. This oligodeoxynucleotide is effective in animal, plant and bacterial cells. Specific end modifications have been described that greatly increase the efficiency of this oligodeoxynucleotide in bacteria. Surprisingly, unmodified oligodeoxynucleotides are as effective as modified nucleotides in mammalian cells, including stem cells in vivo, and chimeric oligos composed of a mixture of deoxynucleotides and 2′-O-methylribonucleotides. It can be as effective or better than nucleotides. |
| priorityDate | 1999-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.