| abstract |
(57) [Summary]nThe present invention relates to a method for rejuvenating normal somatic cells, and a method for producing different types of normal somatic cells having the same genotype as a target normal somatic cell. These cells have particular use in cell and tissue transplantation. Also included are methods for recloning cloned animals, particularly methods for designing the offspring ("ultra-young") of a cloned mammal so that the gene is altered relative to the cloned parent. Is done. These animals are healthier and have favorable properties compared to the cloned parent. Also included are methods of activating endogenous telomerase, EPC-1 activity, and / or the ALT pathway, and / or extending the life span of normal somatic cells or other genes associated with proliferative capacity cell senescence. |