Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 |
filingDate |
2000-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2003503411-A |
titleOfInvention |
Improved chemical synthesis of guanidinium alkaloids |
abstract |
(57) [Summary]nCompounds having cis- or -trans-1-oxo- and 1-iminohexahydropyrrolo [1,2-c] pyrimidine units, for example, as therapeutic agents having antifungal and / or antiviral and / or antitumor activity There is provided an improved method for intensive enantioselective total synthesis of guanidinium alkaloid compounds including 13,14,15-isoclambesidine 800, clambesidine 800 and ptyromicalin A for use. Also disclosed are methods for preparing novel pentacyclic intermediates for preparing the guanidinium alkaloids and homologues of the clambecidin / ptilomicarin family. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4776846-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003514888-A |
priorityDate |
1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |