http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003503363-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2000-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2003503363-A |
| titleOfInvention | Method for selecting a polycation-based bioconjugate suitable for transporting various active substances into the body |
| abstract | (57) [Summary]nThe invention relates to a polycation bioconjugate and a method for producing the same. The novel polycation bioconjugates according to the invention allow the contained polycations to transport various active substances to mammals, that is, to function as carrier molecules, that is, to enhance the biological effect of the transported molecules, and as a result, For example, it is characterized in that it can preferably inhibit the growth of malignant cells, has an antimicrobial effect, or is suitable for gene transfer. Another feature of the polycationic bioconjugates of the invention is that they each comprise an isopolypeptide carrier molecule having an α-amino group as a common characteristic structural element. An enhancer molecule with an appropriate binding function-which may be the same or different-is joined to the connecting molecule-which may be the same or different-by a chemical bond-to a carrier molecule. As a result, polycation bioconjugates synthesized according to the invention have an average "r" between 20 and 400, and "m" = 0, 1, 2, 3,. . k, [(k) Mx] represents an enhancer molecule and / or a connecting molecule joined to the isopolypeptide polycation carrier molecule by a covalent bond (= k), and [(i) Mx] represents an ionic bond (= I) represents an enhancer molecule and / or a connecting molecule bonded to the isopolypeptide polycation carrier molecule, and the enhancer molecule and the connecting molecule having an appropriate functional group for the bonding are the same. Or a separate species (of two or more trees, ie "x" species), and a polycationic bioconjugate of general formula (I) in which enhancer molecules can be joined directly and / or indirectly via connecting molecules. is there. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8796027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006304644-A |
| priorityDate | 1999-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.