| abstract |
The present invention relates to a cationic lipid for gene transfer and a method for producing the same, and more particularly to a cation for gene transfer required for gene therapy or transformation by incorporating an amino acid group such as lysine or ornithine into cholesterol. Disclosed are a lipid, a liposome, and a method for synthesizing the same. According to the present invention, a new type of cationic lipid having low cytotoxicity and high gene transfer efficiency can be provided, and a method for rapidly and efficiently synthesizing various cationic lipids by solid phase synthesis is provided. Can be provided. |