Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0336 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 |
filingDate |
2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2003-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2003501102-A |
titleOfInvention |
Animal models and methods for the analysis of lipid metabolism and the screening of pharmaceuticals and insecticides that regulate lipid metabolism |
abstract |
(57) [Summary]nDrosophila melanogaster and C. elegans have been described that have been genetically modified to express or aberrantly express proteins involved in the sterol regulatory element binding protein (SREBP) pathway. These genetically modified animal models provide identifiable expressions that are useful in assays to study lipid metabolism, other genes involved in lipid metabolism, and compounds that can modify lipid metabolic pathways It has a mold. Also described are methods for studying lipid metabolism in living nematodes using fluorescently labeled fatty acid conjugates, such as BODIPY® fatty acid conjugates. Also described are novel SREBP pathway nucleic acid and protein sequences. |
priorityDate |
1999-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |