abstract |
(57) [Summary]nThe present invention relates to novel compounds and salts thereof in error of all possible isomers of formula (I) as medicaments.nEmbedded imagen (Where Z is -CH 2 -, -SO 2 -, -CO-, -COO-, -CONH- or-(CH 2 ) 2 -NR 3 -Represents an integer 0 or 1; 1 Is hydrogen, aryl, -CH 2 -Aryl, -SO 2 -Aryl, -CO-aryl, heterocycle, -CH 2 -Heterocycle, alkyl or -SO 2 -Represents an alkyl group; 2 Is an alkyl group, a cycloalkyl group or oxygen, sulfur or NR 3 Y represents oxygen, sulfur or NR 3 And D 1 And D 2 May be the same or different and each is a hydrogen atom, a hydroxyl group, a linear or branched alkyl or alkoxy group having up to 6 carbon atoms and NHR 5 Selected from the group or together they are = O or NN-OR 4 To form a group, 1 And D 2 Is hydrogen, hydroxyl, alkyl, alkoxy and NHR 5 Or = O or NN-OR 4 Or R 3 Represents hydrogen, alkyl or cycloalkyl; 4 Represents hydrogen, alkyl, cycloalkyl or aryl; 5 Represents hydrogen, alkyl, cycloalkyl or -COOtBu; 6 Is hydrogen, halogen, hydroxyl, alkyl, alkoxy or NHR 3 Represents ) |