http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003500394-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 |
filingDate | 2000-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2003-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2003500394-A |
titleOfInvention | Reduction of oxiranyl epothilone compounds to olefinic epothilone compounds |
abstract | (57) [Summary] The present invention provides a method for producing an epothilone compound represented by the following formula from an epothilone compound having an oxiranyl component. Embedded image Such a preparation is by reacting the starting compound with a metal or metal-assist reagent. The metal or metal - assisting reagent, a) reactive metallocene; b) [N 2 C ( CO 2 Me) 2, cat Rh 2, (OAC) 4]; c) [N 2 C (CO 2 Me) 2 , cat [(n-C 7 H 15 CO 2) 2 Rh] 2]; d) [Zn-Cu, EtOH]; e) [Mg (Hg), MgBr]; f) Cr; g) [FeCl 3, n-BuLi]; h) [ TiCl 3, LiAlH 4]; i) [TiCl 4, Zn]; j) [WCl 6, LiAlH 4]; k) [NbCl 5, NaAlH 4]; l) [VCl 3, Zn] and m) [WCl 6 , n-BuLi]. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005522461-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007519709-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012121890-A |
priorityDate | 1999-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.