abstract |
(57) [Summary]nThe present invention relates to microgranules insoluble in gastric juice, each containing a gastric proton pump inhibitor other than omeprazole, comprising an active layer containing the active ingredient and an outer layer providing insolubility in gastric juice. The present invention is characterized in that the active layer and the layer providing insolubility in gastric juice each contain a hydrophobic substance selected to increase the storage stability of the microgranules, and the microgranules are composed of an alkaline compound. And ionic surfactants are not contained. |