| abstract |
(57) [Summary] (Revised) [Problem] A disease related to a melatonin receptor having excellent stability, safety and price, for example, poor sleep, insomnia, poor sleep, jet lag, day / night reversal phenomenon, Non 24-hour sleep Composition for prevention or treatment of circadian rhythm sleep disorders such as wakefulness syndrome, time difference syndrome, shift work syndrome, delayed sleep syndrome, inflammatory bowel disorder, sudden constipation, digestive motility disorder related to irritable bowel syndrome Offer things. An agent having affinity for a melatonin receptor, containing an kale, propolis or an extract thereof, an oral composition, a parenteral composition containing these, a food, Medicine. |