abstract |
PROBLEM TO BE SOLVED: To provide an acid-labile active ingredient which is capable of rapidly neutralizing acid in the stomach, which is not coated with an enteric coating and which has an anti-ulcer effect, in particular, a benzimidazole compound. Provided is a solid preparation containing a solid preparation in which the active ingredient has a rapid pharmacological effect and the generation of carbon dioxide is suppressed as much as possible. SOLUTION: An intestine containing an acid-labile active ingredient, particularly a benzimidazole-based compound, and at least one component selected from metal oxides and metal hydroxides and having a disintegration time of 7 minutes or less. Gastric disintegrating solid preparation without a soluble coating. |