http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003306499-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2003-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e28527255ca4d19e6ec9a85613aeba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8318e939aa7880ad9526b2bd6f263908 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdbc4e67a2b32a749bc4a0e46d9163d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c9e39833c1007799e9c456755372a0 |
publicationDate | 2003-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2003306499-A |
titleOfInvention | New RAGE binding substance |
abstract | [57] [Abstract] [Problem] In a state where carbonyl stress etc. is pathologically increased due to a decrease in excretion and metabolic functions such as diabetes, artificial dialysis, various nephropathy, etc., the cause of various vascular lesions such as arteriosclerosis. Separation by contacting a liquid to be treated derived from a body fluid with an adsorbent obtained by immobilizing a substance having affinity for a RAGE binding substance on a water-insoluble carrier and a diabetic complication factor in a body fluid that may contain carbonyl stress products Provide information on how to recover. The solution of the present invention has the following configuration. `` (1) After contacting the adsorbent obtained by immobilizing the RAGE-binding substance-adsorbed ligand on the water-insoluble carrier with the liquid to be treated derived from the body fluid, the adsorbent is sufficiently washed with a washing aqueous solution, and then the adsorbent is further washed. The diabetic complication factor characterized in that it is separated and recovered by bringing it into contact with an aqueous solution for separation and recovery. "" (2) A method for separating and recovering the diabetic complication factor described in the above item (1). " |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009113340-A1 |
priorityDate | 2002-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 483.