| abstract |
(57) [Summary] [Problem] To cope with various skin problems such as skin aging symptoms such as wrinkles and spots caused by external stresses such as aging and ultraviolet rays, decreased skin elasticity, and rough skin, To provide a skin external preparation having a high anti-aging effect and a high effect of restoring epidermal homeostasis. SOLUTION: As a result of screening for a substance having an effective activating effect using an antioxidant effect and an activating effect on dermal fibroblasts and epidermal cells as indices, surprisingly, extraction of Ranunculaceae and its close relatives was carried out. Found that the product has a remarkable antioxidant effect, dermal fibroblast and epidermal cell activation effect, and furthermore, by adding it to a skin external preparation, a skin external preparation with a high anti-aging effect and an effect of restoring epidermal homeostasis can be obtained. completed. |