| abstract |
(57) [PROBLEMS] To antagonize endothelin and have high blood pressure, pulmonary hypertension, acute renal failure, myocardial infarction, angina pectoris, cerebral infarction, cerebral vasospasm, arteriosclerosis, bronchial asthma, gastric ulcer, To provide an endothelin antagonist useful for improvement / treatment of diabetes and the like. An endothelin antagonist containing propolis, kale or an extract thereof, a therapeutic agent for hypertension, a therapeutic agent for heart disease or cerebral cardiovascular disease, a therapeutic agent for renal disease, a therapeutic agent for asthma, a therapeutic agent for ulcer, a therapeutic agent for diabetes, Oral compositions containing these, Food, medicine. |