| abstract |
PROBLEM TO BE SOLVED: To provide an amino alcohol having an excellent immunosuppressive action. And pharmacologically acceptable salts thereof, and pharmaceutically acceptable esters thereof, and pharmaceutical compositions containing them. SOLUTION: General formula (I) Wherein R 1 and R 2 are a hydrogen atom, a protecting group for an amino group, etc .; R 3 is a hydrogen atom, a protecting group for a hydroxy group, etc .; 4 is a lower alkyl group; n is an integer of 1 to 6; X is an oxygen atom or a nitrogen atom which is unsubstituted or substituted by a lower alkyl group; Y is an ethylene group; Z is C 1 -C 10 alkylene group or the like; R 5 is, ant - group, substituted ants - Le group; R 6 and R 7, such as a hydrogen atom; provided that when R 5 is a hydrogen atom, Z is a single bond and Linear C 1 -C 10 Shows a group other than an alkylene group. ], A pharmacologically acceptable salt thereof, an ester thereof or another derivative thereof. |