| abstract |
PROBLEM TO BE SOLVED: To provide a method for producing 1,4-dicarbonyl compound (5) useful as an intermediate for producing pharmaceuticals, agricultural chemicals, functional materials and the like under industrially advantageous conditions. SOLUTION: An organic zinc compound (2), a conjugated carbonyl compound (3) and a trialkylsilyl halide (4) are reacted in the presence of a palladium catalyst, a lithium salt and carbon monoxide, and then treated with an acid. Embedded image (Wherein, R 1 represents a halogen atom, an alkyl group, or the like; n represents 0 or an integer of 1 to 5, X represents a chlorine atom, a bromine atom or an iodine atom, R 2 represents a hydrogen atom, an alkyl group, or the like; R 3 and R 4 each represent a hydrogen atom; R 5 , R 6 and R 7 each represent an alkyl group, and Y represents a chlorine atom, a bromine atom or an iodine atom. ) |