| abstract |
(57) Abstract: A novel biaryl compound having a melanocortin receptor agonistic or antagonistic action. SOLUTION: Formula (I) (Wherein ring A and ring B may be further substituted 6 The membered aromatic ring, X is -CONR 4 -, - SO 2 NR 4 -, - CH 2 NR 4 - (R 4 is a hydrogen atom, and a hydrocarbon group which may be substituted) and the like, Y Represents a spacer having 1 to 12 atoms, Z is -CONR 6 -, - CO- (R 6 is a hydrogen atom, a hydrocarbon which may be substituted hydrogen group or an optionally substituted heterocyclic group) and the like, R 1 is optionally substituted A good amino group, R 2 is an optionally substituted hydrocarbon group, R 3 is an optionally substituted hydrocarbon group, etc., and R 5 is an optionally substituted hydrocarbon group, etc. Or a salt thereof. |