| abstract |
(57) [Problem] To provide a means for improving the thermostability of hydrogenase. SOLUTION: In the hydrogenase, a method for producing a thermostable hydrogenase characterized by substituting a specific amino acid with isoleucine, a thermostable hydrogenase produced by the method, a DNA encoding the thermostable hydrogenase, and the DNA are included. A thermostable hydrogenase producing microorganism, a method for producing the microorganism, and a method for producing a thermostable hydrogenase using the microorganism. |