abstract |
(57) [Summary] (With correction) [Problem] (R) -1-cyclopropyl-8-difluoromethoxy-7- (1-methyl-2,3-dihydro-1H) -5-isoindolyl) -4-oxo-1,4-dihydro-3-quinoline-carboxylic acid (hereinafter abbreviated as T-3811). SOLUTION: 2-[(1R) -1-methyl-2-trityl-2,3-dihydro-1H-5-isoindolyl]- The unsolvated 1,3,6,2-dioxaazaborocan is It is most suitable as a production intermediate of T-3811. |