abstract |
(57) [Summary] (With correction) [PROBLEMS] To provide a biocompatible biodegradable polyester and a novel sustained-release pharmaceutical composition. A polyester comprising one or more free COOH groups and having a carboxyl to hydroxyl ratio greater than 1, comprising L-lactic acid, D-lactic acid, DL-lactic acid, malic acid, citric acid, tartaric acid, ε-caprolactone, p-dioxanone, ε-caproic acid, alkylene oxalate, cycloalkylene oxalate, alkylene succinate, β-hydroxybutyrate, substituted or unsubstituted trimethylene carbonate 1,5-dioxepane-2-one, 1,4-dioxepane-2-one, glycolide, glycolic acid, L-lactide, D-lactide, DL-lactide, meso-lactide, and any optical thereof Said polyester comprising a member selected from the group consisting of active isomers, racemates or copolymers, wherein tartaric acid is a member of the polyester. |