| abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide a method for producing a compound represented by the formula 1 (wherein, R 1 represents a C 1 -C 6 alkyl group). SOLUTION: a) A compound of the formula 2 is reacted with a Grignard reagent, and b) A alkanesulfonyl halide or an alkanesulfonyl anhydride is reacted. The intermediate (2), which is useful for the preparation of pyridyl-substituted pyrazoles for use in the treatment and alleviation of inflammation and other inflammation-related disorders (eg, arthritis, neurodegeneration and colorectal cancer), is selective and advantageous. Obtained at a rate. |