abstract |
PROBLEM TO BE SOLVED: To provide an antioxidant having a strong specific free radical scavenging action and an antioxidant action for protecting mammalian cells and tissues in cosmetics and pharmaceutical preparations, Provided are a method for producing the same and a cosmetic preparation containing the same. It is produced by a reaction of 2- (3,4-dihydroxyphenyl) ethylamine with heterocumulene (isocyanic acid or isothiocyanic acid compound), and the like. 2- (3,4-dihydroxyphenyl) ethyl-substituted carbonic acid derivatives of the formula I. The derivative has a strong free radical scavenging action and an antioxidant action and is useful for cosmetic and pharmaceutical preparations. [R1 is a hydrogen atom, a lower alkyl group or the like; X2 and X3 are S, O or NH, and R2 is a C1-22 alkyl group optionally substituted by O, etc. |