abstract |
(57) [Problem] To provide a method for easily and effectively improving the thermostability of an enzyme and expressing high enzyme activity at a high temperature. A method for increasing the activity of an enzyme at a high temperature, wherein a substance having a chaperone action in a reaction solution containing the enzyme, for example, amino acids such as betaine and sarcosine, glycerol, and ethylene glycol A method in which a polyhydric alcohol and a chaperonin-like protein are present. |