| abstract |
(57) [Problem] To improve an unpleasant feeling of use when applying an ophthalmic composition to an ocular mucosa. SOLUTION: Xanthines (caffeine, theophylline, theobromine, proxyphylline, pentoxifylline, etc.) are combined with an ophthalmic solution with unpleasant eye irritation or pain and an unpleasant taste when applied to the ocular mucosa. By doing so, such an uncomfortable feeling of use can be improved. According to the method of the present invention, it is possible to provide an ophthalmic composition such as an eye drop, an eye wash, a liquid for contact lenses, etc., which is excellent in the feeling of use, and it is possible to improve the compliance of the user. |