abstract |
PROBLEM TO BE SOLVED: To provide a therapeutic agent for neuronal degeneration which can enhance the function of cholinergic neurons, striatal neurons and sensory neurons in mammals and has no cytotoxicity. A novel K-252a derivative, and A novel bis-N-substituted derivative of staurosporine is provided. In addition, a novel staurosporine derivative or K- Also provided is a method of treating diseased neuron cells, comprising administering any of the specialized functional derivatives of 252a. |