| abstract |
(57) [Summary] [Problem] New 3- with potassium channel opening action A hydroxypyridine derivative is provided. SOLUTION: The formula: [Wherein, A represents a phenyl group which may have a substituent (provided that the ortho position is unsubstituted), and B represents -OH,- (R 2 ) represents a 2-pyridyl group which may further have a substituent other than m and → (O) n , wherein R 2 is one selected from a nitrogen atom, an oxygen atom, a sulfur atom and a phosphorus atom or Polar groups containing two or more heteroatoms (provided that C 1-4 shows the excluding alkoxy group), m is an integer of 1 to 3, and when m is 2 or 3, substituents R 2 may be the same or different, n represents 0 or 1, R 1 represents an optionally substituted branched C 3-8 alkyl group or an optionally substituted C 3-8 cycloalkyl group, X is an oxygen atom or NR 3 (R 3 is a hydrogen atom or C 1-4 Which represents an alkyl group) or a salt thereof. |