| abstract |
(57) [PROBLEMS] To provide a method for enhancing the efficacy of a local anesthetic component, an antipruritic component, an antihistamine component or an anti-inflammatory component contained in a medicinal solution in an aerosol preparation comprising a medicinal solution and a propellant, and a composition for enhancing the medicinal effect As well as aerosol formulations with enhanced efficacy. In preparing an aerosol formulation, A) at least one active ingredient selected from the group consisting of a local anesthetic component, an antipruritic component, an antihistamine component, and an anti-inflammatory component, B) Urea, glycyrrhizic acid, glycyrrhizic acid salt, A derivative of glycyrrhizic acid, glycyrrhetinic acid, a salt of glycyrrhetic acid, a derivative of glycyrrhetic acid, an allantoin and an allantoin derivative, C) an essential oil component, and D) a propellant are blended. |