http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003064094-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_996c9f30d41e89e8184193c7a23b6bac http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11a792d7816d4692078e29ef27bfa056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7e81a30f5e435049a6050f4d39f33d0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
filingDate | 2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67eb487906f0710349dd60c899e20153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64558eb5ff5b0c34af8c5c7874c66f18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a178b368598edd9b8c384b4f6e74a5a9 |
publicationDate | 2003-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2003064094-A |
titleOfInvention | New cyclic peptide |
abstract | [PROBLEMS] Cyclic peptides are known to have various physiological activities including protease inhibitors. And there is a possibility that a cyclic peptide that mimics the β-turn structure can be a protease inhibitor. However, the conformation of the cyclic peptide has a high degree of freedom, and in particular, the three-dimensional structure is lost in an aqueous solution, and the expected protease inhibitory ability may not be exhibited. Therefore, it is strongly desired that the conformation of the cyclic peptide be regulated and immobilized. To solve the above-mentioned problems, an aromatic ring and two carbonyl groups are introduced into a cyclic peptide to regulate the conformation of the cyclic peptide and immobilize it. By changing the aromatic ring, various conformations are possible. Therefore, the present invention can provide various bioactive cyclic peptides. |
priorityDate | 2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.