abstract |
PROBLEM TO BE SOLVED: To provide a zinc (II) complex having low toxicity, high insulin-like activity, and which can be effectively used as a hypoglycemic agent for the prevention and treatment of diabetes, and a method for producing the same. It is an object of the present invention to provide a hypoglycemic agent, a pharmaceutical preparation containing the complex, which is useful as a prophylactic / therapeutic agent for diabetes, and foods containing the complex, such as health foods and health supplements. The present invention provides an aminoalkylpyridine, Bis optically active amino acids, bisaminoalkylcarboxylic acids, oligopeptides, oligopseudopeptides, disubstituted aminocarboxylic acids, α- and β-oxycarboxylic acids, vitamins and glutamine derivatives as ligands A hypoglycemic agent comprising a zinc (II) organic complex having the same as the above, a pharmaceutical composition useful as a remedy for diabetes comprising the complex, and foods such as health foods and health supplements comprising the complex About. |