abstract |
(57) Abstract: An apparatus for sampling at least one kind of biological fluid component and measuring at least one kind of target component in the biological fluid is provided. The device includes at least one microneedle having an open tip used to penetrate the skin to a predetermined depth, wherein pain and bleeding are minimized. To be fixed. The apparatus further comprises a hydrophilic gel in the microneedle for sampling each component of the biological fluid, and an electrochemical cell for measuring the concentration of a target component in each component of the sampled biological fluid. It has. In certain embodiments, the electrochemical cell is integrated with the microneedle so that sampling and measurement steps are performed entirely in situ. In another embodiment, the electrochemical cell is located outside the microneedle at its proximal end. In addition, component sampling and measurement systems, methods and kits are provided. |