| abstract |
[PROBLEMS] To provide a novel fluorescent nucleotide useful for labeling a nucleic acid. SOLUTION: X—Y—Z [X represents a residue such as a natural or non-natural nucleotide, and is bonded to Y at the base moiety in the residue; Y is a divalent linking group or a single bond Indicates; Z represents the formula (I) (R 1 to R 4 represent an alkyl group; V 1 to V 6 Represents a hydrogen atom or a substituent; L 1 to L 7 represent a methine group; W represents an oxygen atom, a sulfur atom, -C (R 3 ) (R 4 )-or- N (R 5 ) —, (R 3 to R 5 each represents an alkyl group); Q represents a nitrogen atom or —C (V 7 ) — (V 7 represents a hydrogen atom or a monovalent substituent); M represents a counter ion; m is necessary to neutralize the charge of the molecule. Is a monovalent group derived from a compound represented by the formula: s, t, or u represents 0 or 1, and is bonded to Y by a reactive group present in R 1 or R 2 A fluorescent nucleotide represented by [Chemical 1] |