abstract |
PROBLEM TO BE SOLVED: To provide a nano-emulsified particle stabilized according to the present invention, when a bioactive substance is contained therein, since the stability of the bioactive substance is also improved. An external preparation having excellent effects such as antioxidation, whitening, suppression of skin wrinkles, skin moisturization, exfoliation, and protein synthesis effect can be provided depending on the type of the physiologically active ingredient. SOLUTION: The present invention provides a method for stabilizing emulsified particles having a size of several to several tens of nanometers produced using lecithin as an emulsifier by using a tocopherol derivative represented by the following chemical formula (I), and containing the nanoemulsified particles. And a skin external preparation composition. Embedded image (Wherein R 1 , R 2 and R 3 are methyl groups, at least one of R 1 , R 2 and R 3 is a methyl group, and A is CH 2 --CH (CH 3 )-or CH = C (CH 3 )-) |