http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003012503-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_718a40268150a2c24e6f99a6375a8643 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate | 2001-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_447e7d8e70a1bdbe7b58992a1c8062cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00698fdfb7953b9b066e6c72a7563cc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee115c5ddcde31eb14288606bc834ac3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12fe806bebc8982484e523982eeef216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b49e18364743e50b61f87371ee82ac0 |
publicationDate | 2003-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2003012503-A |
titleOfInvention | Methods for immobilizing lipid vesicles and genes |
abstract | (57) [Problem] A liposome used as a conventional gene carrier has problems in stability and metabolism, and is expensive and expensive. Solving the problem that it is difficult to use as DS, stability, Provided is a method for immobilizing lipid vesicles and genes as DDS which is excellent in metabolism and is inexpensive. SOLUTION: A cationic peptide lipid is added to an artificial lipid constituting a lipid vesicle, the surface of the lipid vesicle is made to have a positive polarity so that DNA can be easily attached thereto, and a nucleic acid binding protein such as histone is added to a plasmid gene. A method for immobilizing a gene on a lipid vesicle after improving the transfection efficiency realizes a gene immobilization method that is excellent in stability and metabolism, is inexpensive, and has high transfection efficiency. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010193875-A |
priorityDate | 2001-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.