abstract |
(57) [Summary]nThe present invention relates to a compound of formula (I), a pharmaceutically acceptable salt of said compound, a pharmaceutically acceptable solvate of said compound, or a solvate of said salt. These compounds inhibit carboxypeptidase U and can therefore be used in the prevention or treatment of carboxypeptidase U-related diseases. In a further aspect, the invention provides a compound of the invention for use in therapy; a method of making such a novel compound; at least one compound of the invention, or a pharmaceutically acceptable salt or a pharmaceutically acceptable salt of said compound. A pharmaceutical composition comprising a solvate as an active ingredient; and the use of the active compound of the present invention in the manufacture of a medicament for the above medical uses. |