| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate |
2000-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2002-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2002542166-A |
| titleOfInvention |
Fab'-epitope complex of HIV-1 cross-neutralizing monoclonal antibody 2F5 |
| abstract |
(57) [Summary]nExtensive conservation of the viral envelope protein gp41 of the Fab 'fragment of Mab 2F5, a neutralizing agent that is an effective neutralizer for both laboratory strains and the primary clinical isolates of many isogenic strains of HIV-1 Both complexed and uncomplexed crystal structures with the peptide sequence ELDKWAS have been solved and the properties of the peptide-protein interaction determined. In connection with such a determination, the peptidomimetic is controlled into a three-dimensional structure that confers increased antigenicity to its epitope sequence. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008507554-A |
| priorityDate |
1999-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |