| abstract |
(57) [Summary]nThe present invention provides human apoptosis regulatory proteins (avens) and polynucleotides that identify and encode avenues. The present invention also generally provides engineered expression vectors and host cells comprising a nucleic acid sequence encoding an aven, as well as methods for producing aven. The present invention also provides agonists, antibodies, or antagonists that specifically bind to aven and methods of using them in the prevention and treatment of diseases associated with aven expression. Further, the present invention provides the use of an antisense molecule against a polynucleotide encoding an aven for the treatment of a disease associated with aven expression. The present invention also provides diagnostic assays that use antibodies that specifically bind to a polynucleotide or fragment or complement thereof and aven. |