| abstract |
(57) [Summary]n4- and 5-oxacyclopent-2-en-1-one have significant activity in activating HSF and in inhibiting NF-κB. They include a wide range of disorders, including virus-mediated disorders, bacterial-mediated disorders, radiation-mediated disorders (eg, due to UV radiation), inflammatory disorders, disorders of the immune system, ischemia, arteriosclerosis, disorders including cell proliferation (eg, cancer). ), Disorders associated with cell damage or cell killing (oxidative cell damage) and diabetes. |