| abstract |
(57) [Summary] Formula (I) or (I ′): Wherein R x is a substituent as defined herein; Q 1 is optionally substituted phenyl, and Q 1 carries a substituent of formula (Ia), wherein , X, Y 1 , Y 2 , Z, n and m are as defined herein; -NQ 2 contains one heteroatom and optionally further heteroatoms Pyrimidine Derivatives which are substituted heterocyclic moieties]; or pharmaceutically acceptable salts or in-vivo hydrolysable esters thereof, are useful as anticancer agents. These manufacturing processes and pharmaceutical compositions containing them are described. |