http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002539091-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-32 |
| filingDate | 2000-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002539091-A |
| titleOfInvention | Purification method of human growth hormone |
| abstract | (57) [Summary]nA method for purifying human growth hormone (hGH) from deamidated hGH, oxidized hGH, or both. The method comprises the step of forming a metal cation complexed hGH composition enriched in natural hGH under conditions in which deamidated hGH, oxidized hGH, or both, do not form a complex with a metal cation at all or hardly. And isolating the metal cation complexed hGH composition from deamidated hGH, oxidized hGH or a combination thereof. The method may further comprise the step of releasing purified hGH from the complex. Alternatively, metal cation conjugated hGH can be encapsulated within a biocompatible polymer for sustained release of hGH. The purification method can be performed one or more times using hGH released from the metal cation complexed hGH composition, depending on the desired hGH purity. |
| priorityDate | 1999-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.