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filingDate 2000-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2002-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002537851-A
titleOfInvention In vitro test method for active substances, device and use thereof
abstract (57) [Summary]nA cell culture vessel having at least an inner chamber and an inner wall, and having first and second membrane systems provided in the inner chamber, wherein a cell culture chamber is formed between the membrane system and the inner wall of the inner chamber. Preparing the cells as a cell culture in a cell culture chamber, and loading the cell culture medium, supplying a liquid nutrient medium into the cell culture chamber using the first membrane system, and Removing the metabolites from the process, supplying the at least one gaseous medium into the cell culture chamber using the second membrane system, metering at least one active substance into the cell culture chamber, An in vitro method for testing an agent on cells, comprising metering in according to a predetermined agent concentration-time-time course, and monitoring cell viability. Furthermore, a device and the use of said device for testing the effect of idarubicin on the leukemia cell line CCRF CEM.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729536-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016503299-A
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Total number of triples: 26.