abstract |
(57) Abstract: Substituted 1,2,4-triazolo [4,3-b] pyridazine derivatives having an optionally substituted phenyl ring at the 3-position and a C-substituted triazolyl-methoxy moiety at the 6-position are GABA A receptors And especially ligands with high affinity for its α2 and / or α3 subunits, and thus are useful for the treatment and / or prevention of diseases of the central nervous system, including anxiety and convulsions. |