abstract |
(57) Abstract: Including the pharmaceutically acceptable salts, all stereoisomers and prodrugs, the formula: Wherein n is an integer of 1 to 5; Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 5a , R 6 , R 8 , R 9 and R 10 As defined herein) having the structural formula: These compounds are inhibitors of factor Xa and are therefore useful as anticoagulants. Methods for treating cardiovascular diseases associated with thrombosis are also provided. |