| abstract |
(57) [Summary]nAn easy method for preparing diketide thioesters and triketide thioesters is disclosed. The resulting thioester can be used as an intermediate in the synthesis of the desired polyketide, and is ultimately present in the side chain on the resulting polyketide, and thus used to further manipulate the polyketide to form a derivative. The resulting functional group may be included. The polyketides produced can also be modified by glycosylation, hydroxylation, and the like. This modification produces new polyketides and their derivatives and modified forms. |