abstract |
SUMMARY OF THE INVENTION The present invention provides an anticoagulant coating composition for blood contacting surfaces. The coating comprises a covalent complex of 1 to 30 hydrophobic silyl moieties of formula (I) directly attached to the heparin molecule by a covalent bond, wherein R 1 is C 1-8 alkyl or C 1 A 6-32 aryl group, wherein R 2 is each independently selected from the group consisting of C 1-8 alkyl and C 6-32 aryl, R 3 is N or O, and n is a number from 1 to 10. Is). |