| abstract |
(57) [Summary] The present invention relates to a novel method for producing a pharmaceutically active compound and an intermediate thereof. The (-) trans form (paroxetine) of 4- (4'-fluorophenyl) -3- (3 ', 4'-methylenedioxyphenoxymethyl) piperidine is an important compound having antidepressant and antiparkinson properties. This compound is used as a hydrochloride, especially for the treatment of depression, obsessive compulsive disease (OCD) and panic. Methods for preparing paroxetine acetate and analogs thereof are described. Embedded image |