abstract |
(57) Abstract The present invention relates to novel peptides that are biologically active as ligands for α v β 6 integrins. The peptides have a common structural motif, namely Asp Leu Xaa Leu- or a preferred form of Arg Xaa Asp Leu Xaa Xaa Leu Arg-(where Xaa represents any amino acid residue). The peptide of the present invention can be used as an effective α v β 6 integrin receptor inhibitor, and thus can be used in the treatment of various diseases and medical conditions. |