http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002533060-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70535 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
filingDate | 1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002533060-A |
titleOfInvention | Crystalline form of Fc epsilon receptor alpha chain, 3-D model thereof, and uses thereof |
abstract | (57) [Summary]nThe present invention includes three-dimensional models of antibody receptor proteins, such as, for example, FcεRIα proteins, and methods of creating such models. Further, the present invention provides a method for producing such a mutant protein, which may use a mutant protein having increased stability and / or antibody binding activity, and preferably information obtained from the three-dimensional model of the present invention. including. Also included are nucleic acid sequences encoding the mutated proteins of the invention, and the use of these sequences to produce such mutated proteins. Also included is the use of this model to identify compounds that inhibit the binding of the antibody receptor protein to the antibody. The invention further includes the use of such mutant proteins and inhibitory compounds in methods of diagnosing and protecting against, for example, allergic and other abnormal immune responses in animals. |
priorityDate | 1998-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.